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Abstract. Climate change negatively impacts food security and contributes to desertification and land degradation globally. With the projected population growth, estimated at 10 billion people by 2050, and the reduction of land and water for agriculture, the great challenge of the future will be to meet the world's food needs. Despite increasing water scarcity and deteriorating water quality, irrigated agriculture is fundamental in meeting current and future food production needs. The environmental problems of the Mediterranean areas are of great importance due to the continuous growth of tourism and the concentration of economic activities along the coast. Meanwhile, rural regions suffer from depopulation and the abandonment of productive farming activities. Therefore, this study aims to promote alternative Mediterranean farming systems based on agroecological principles to counteract the growing pressure from destroying natural resources and climate change. These goals are achieved within Smart agriculture optimization to Climate change adaption (CICLICA) through the application of advanced agricultural practices in three main areas: a) water conservation strategies, including poor quality water and the use of non-conventional water for irrigation, organic mulching and the use of subsurface precision drip irrigation technology; b) biotechnological techniques (water quantity and quality management during irrigation with superabsorbent polymers); and c) using genetic regulation of water tolerance to introduce new alternative crops, increase new ecosystem services, improve soil health and ecological footprint. As Methods for determining the suitability of these three main areas within the project CICLICA, a life cycle assessment (LCA) will be done. This LCA followed the guidelines described in the standard EN ISO 14044 version 2006 to determine the first results about Smart agriculture optimization using eight environmental impact categories.