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Abstract. Low energy and low protein diet are provided for laying hens in the breeding stage to reduce the feeding cost. 504 Hyline brown laying hens of 11-week age were chosen and randomly divided into 6 groups. Each group had 7 repeats. One repetition contained 12 hens. Contrast groups 1 and 2 were feed with normal energy and protein. Enzymic preparations were added to contrast group 1. The negative control group was feed with 80kcal energy and 1% protein reduction. Different enzymic preparations were added in experimental groups feed based on the negative control group diet. The experiment lasts for six weeks. And the results show: when the ration protein for young chicken drop and without enzymic preparations, its feed conversion ratio is lowest, but the difference of weight food consumption and the feed-weight ratio does not reach a significant difference (P>0.05). Low energy and low protein diet had no significant effect on young laying hens‘ antibody level of H9 and H5-4 (P>0.05). However, in the third week, the ND antibody level from high to low is group 4, group 0, group 3, group 1, group 5 and group 2. In the sixth week, the significant differences of the ND antibody levels were not found between different groups, but zero groups and forth groups have a tendency high than other groups (P=0.098). In the third week, serum uric acid level from low to high is group 3, group 5, group 2, group 0, group 4 and group 1, but the difference is not significant (P= 0.12). In the sixth week, no significant difference was found in serum uric acid level of each young laying hens groups. It can be concluded from the above results that: on the basis of the existing formula with 80 kcal energy and 1% protein drop and enzyme preparation add, there is a positive effect for antibody level and protein metabolism of young hens, and the cost of feed is cut down to 80~100 yuan per ton. But few negative influences exist for production performance, maybe energy is not enough. More experiments need to be done for further verification. Enzyme preparation A and B have better effects.