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Anaerobic co-digestion of swine manure and corn stover for biogas production has been studied in two completely-mixed and semi-continuously fed reactors (Reactor 1 and Reactor 2). Each reactor had a working volume of 14 liters and was operated at 35C, a hydraulic retention time of 25 days, and an agitation speed of 120 rpm. Initially the reactors were operated as duplicates and each was fed with 560 ml of swine wastewater per day. After a stable performance had been achieved in both reactors with almost the same results, corn stover was added to Reactor 2 to get a Carbon to Nitrogen ratio (C:N) of 10:1. Since then 560 ml of swine wastewater and 14 g of corn stover have been added to Reactor 2 every day to keep the C:N ratio at 10:1. In the meantime Reactor 1 has been fed the same as previously.