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This paper presents an overview of the use of wind pressure coefficients in modeling natural greenhouse ventilation. The research on pressure coefficients is limited. Most studies have used other methods to determine ventilation rates such as tracer gas techniques. Several models have been developed and validated that utilize pressure coefficients to predict air exchange rates. However, there is still lack of data on pressure coefficients. The authors are currently involved in a research project that uses computational fluid dynamics (CFD) to determine pressure coefficients at vent openings for a naturally ventilated greenhouse. The CFD determined pressure coefficients will be used in a program by Brocket and Albright (1987) to allow real time ventilation rates.