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Mississippi broiler industry produces about one million metric tons of broiler litter annually. Producers are responsible for disposing of the litter in an environmental safe manner. Most of the litter is disposed of through land application that must comply with federal, state and local laws. The upland soils of Mississippi need annual applications of N, P, and K for cotton production. A two-year study was conducted comparing litter with inorganic nitrogen at the North Mississippi Branch Station. The soils were silty loam having less than one-percent organic matter. Nitrogen rates of 0, 33, 66, 99, and 132 kg/ha and litter rates of 4.5, 9, 13.4 t/ha were compared in a randomized complete block design with four replications. Results suggest broiler litter of 9 metric tons/ha provided the needed nitrogen requirement for cotton production in the upland soils.