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A negative ionization system was installed and evaluated in two identical swine grower/finisher rooms, an experiment and a control. It was confirmed that ionization reduced the modified respirable and inhalable dust counts by as much as 46%. The efficiency of the modified respirable and inhalable dust reduction decreased as the ventilation increased, and decreased with time due to the accumulation of dust on surfaces. The mean electrostatic voltage of walls, ceiling and floor in the experimental room was 319 V compared with 137 V in the control room. The high voltage in the experimental room did not present a hazard to operators but likely had an adverse effect on the dust settling.